Applied biopharmaceutics & pharmacokinetics / Leon Shargel and Andrew B. C. Yu

By: Contributor(s): Material type: TextTextPublication details: [Place of publication not identifed] : Prentice-Hall International Inc., c1999Edition: Fourth editionDescription: xiv, 768 pages : illustrations ; 26 cmISBN:
  • 838502784
Subject(s): LOC classification:
  • RM 301.4 .S53 1999
Contents:
Mathematical fundamentals on pharmacokinetics -- introduction to biopharmaceutics and pharmacokinetics -- one compartment model; physiological factors relating to drug absorption -- biopharmaceutic considerations in drug product design -- modified release drug products -- delivery of biotechnical products and targetted drug delivery systems -- pharmacokinetics of drug absorption -- bioavailability and bioequivalence -- multicompartmental models -- drug distribution and protein binding -- drug clearance; drug metabolism and hepatic clearance -- pharmacokinetics after intravenous infusion -- pharmacokinetics after multiple dosing -- non-linear pharmacokinetics -- introduction to clinical pharmacokinetics -- application of pharmacokinetics to clinical situations -- relationship between pharmacokinetic parameters and pharmacologic response -- physiologic pharmacokinetic model and statistical moment -- computer applications in pharmacokinetics -- biopharmaceutics and pharmacokinetic studies in drug development
Summary: This work emphasizes the application and understanding of core areas involving bioavailability, population pharmacokinetics, pharmacodynamics, metabolism and drug delivery.
Item type: Books
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Holdings
Item type Current library Home library Collection Call number Copy number Status Date due Barcode
Books Books National University - Manila LRC - Main General Circulation Pharmacy GC RM 301.4 .S53 1999 (Browse shelf(Opens below)) c.1 Available NULIB000003893

Includes index.

Mathematical fundamentals on pharmacokinetics -- introduction to biopharmaceutics and pharmacokinetics -- one compartment model; physiological factors relating to drug absorption -- biopharmaceutic considerations in drug product design -- modified release drug products -- delivery of biotechnical products and targetted drug delivery systems -- pharmacokinetics of drug absorption -- bioavailability and bioequivalence -- multicompartmental models -- drug distribution and protein binding -- drug clearance; drug metabolism and hepatic clearance -- pharmacokinetics after intravenous infusion -- pharmacokinetics after multiple dosing -- non-linear pharmacokinetics -- introduction to clinical pharmacokinetics -- application of pharmacokinetics to clinical situations -- relationship between pharmacokinetic parameters and pharmacologic response -- physiologic pharmacokinetic model and statistical moment -- computer applications in pharmacokinetics -- biopharmaceutics and pharmacokinetic studies in drug development

This work emphasizes the application and understanding of core areas involving bioavailability, population pharmacokinetics, pharmacodynamics, metabolism and drug delivery.

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