Biopharmaceutics and clinical pharmacokinetics / Milo Gibaldi

By: Material type: TextTextPublication details: Philadelphia, Pennsylvania : Lea & Febiger, c1991Edition: Fourth editionDescription: x, 406 pages : illustrations ; 27 cmISBN:
  • 812113462
Subject(s): LOC classification:
  • RM 301.4 .G53 1991
Contents:
Introduction to pharmacokinetics -- Compartmental and noncompartmental pharmacokinetics -- Gastrointestinal absorption--biologic considerations -- Gastrointestinal absorption--physicohemical considerations -- Gastrointestinal absorption--role of the dosage forms -- Nonoral medication -- Prolonged-release medication -- Bioavailability -- Drug concentration and clinical response -- Drug disposition--distribution -- Drug disposition--elimination -- Pharmacokinetic variability-- body weight, age, sex, and generic factors -- Pharmacokinetic variability--disease -- Pharmacokinetic variability--drug interactions -- Individualization and optimization of drug dosing regiments
Summary: This updated introduction to the clinical applications of pharmacokinetics looks at gastrointestinal absorption, prolonged release medication, and drug disposition. The effects of disease, weight, age, sex and genetic factors on pharmacokinetic variability and drug response are detailed. Bioequivalence and regulatory considerations for generic drug.
Item type: Books
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Item type Current library Home library Collection Call number Copy number Status Date due Barcode
Books Books National University - Manila LRC - Main General Circulation Pharmacy GC RM 301.4 .G53 1991 (Browse shelf(Opens below)) c.1 Available NULIB000015277

Includes bibliographical references and index.

Introduction to pharmacokinetics -- Compartmental and noncompartmental pharmacokinetics -- Gastrointestinal absorption--biologic considerations -- Gastrointestinal absorption--physicohemical considerations -- Gastrointestinal absorption--role of the dosage forms -- Nonoral medication -- Prolonged-release medication -- Bioavailability -- Drug concentration and clinical response -- Drug disposition--distribution -- Drug disposition--elimination -- Pharmacokinetic variability-- body weight, age, sex, and generic factors -- Pharmacokinetic variability--disease -- Pharmacokinetic variability--drug interactions -- Individualization and optimization of drug dosing regiments

This updated introduction to the clinical applications of pharmacokinetics looks at gastrointestinal absorption, prolonged release medication, and drug disposition. The effects of disease, weight, age, sex and genetic factors on pharmacokinetic variability and drug response are detailed. Bioequivalence and regulatory considerations for generic drug.

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