000 01826nam a2200229Ia 4500
003 NULRC
005 20250520094918.0
008 250520s9999 xx 000 0 und d
020 _a3540564314
040 _cNULRC
050 _aQP 552.P4 .B63 1993
100 _aBodanszky, Miklos
_eauthor
245 0 _aPrinciples of peptide synthesis /
_cMiklos Bodanszky.
250 _aSecond, revised edition.
260 _aBerlin :
_bSpringer-Verlag,
_cc1993
300 _axii, 329 pages :
_billustrations ;
_c24 cm.
504 _aIncludes bibliographical references and index.
505 _aActivation and coupling -- Reversible blocking of amino and carboxyl groups -- Semipermanent protection of side chain functions -- Side reactions in peptide synthesis -- Tactics and strategy in peptide synthesis -- Techniques for the facilitation of peptide synthesis -- Recent developments, new trends.
520 _aPrinciples of Peptide Synthesis is a very successful book by one of the pioneers of contemporary bioorganic synthesis. Its first edition proved a valuable source that is kept close to the work bench for frequent consulting. Any researcher planning the formation of the peptide bond, be it for the synthesis of a peptide chain or a cyclic peptide, benefits from the author's experience. The concise and critical treatment of the steps involved: protection, activation and bond formation require careful planning to avoid racemization and undesired side reactions. The second edition has been completely revised and updated. New procedures that have been developed since the first edition was published and that did not fit into the original are added in a separate chapter. This separation of old and new make it possible to assess new ideas and discern novel trends.
650 _aPEPTIDES -- SYNTHESIS
942 _2lcc
_cBK
999 _c6083
_d6083