000			02311nam a2200241Ia 4500
003			NULRC
005			20250520102923.0
008			250520s9999 xx 000 0 und d
020			_a9780199697397
040			_cNULRC
050			_aRS 403 .P38 2013
100			_aPatrick, Graham L. _eauthor
245		3	_aAn introduction to medicinal chemistry / _cGraham L. Patrick
250			_aFifth edition.
260			_aOxford, United Kingdom : _bOxford University Press, _cc2013
300			_axxiii, 789 pages : _bcolor illustrations ; _c27 cm.
365			_bUSD58.45
504			_aIncludes index.
505			_aDrugs and drug targets -- an overview -- Drug targets : structure and function -- Protein structure and function -- Enzymes: structure and function -- Receptors: structure and function -- Receptors and signal transduction -- Nucleic acids: structure and function -- Pharmacodynamics and pharmacokinetics -- Enzymes as drug targets -- Receptors as drug targets -- Nucleic acids as drug targets -- Miscellaneous drug targets -- Pharmacokinetics and related topics -- Statins -- Drug discovery, design, and development -- Drug discovery: finding a lead -- Drug design: optimizing target interactions -- Drug design: optimizing access to the target -- Getting the drug to market -- The design of ACE inhibitors -- Artemisinin and related antimalarial drugs -- The design of oxamniquine -- Tools of the trade -- Combinatorial synthesis -- Computers in medicinal chemistry -- Quantitative structure-activity relationships (QSAR) -- De novo design of a thymidylate synthase inhibitor -- Selected topics in medicinal chemistry -- Antibacterial agents -- Antiviral agents -- Anticancer agents -- Cholinergics, anticholinergics, and anticholinesterases -- Drugs acting on the adrenergic nervous system -- Opioid analgesics -- Antiulcer agents -- Steroidal anti-inflammatory agents -- Design of a novel antidepressant.
520			_aRenowned for its clear and accessible writing style, An Introduction to Medicinal Chemistry 6th edition is widely regarded as the leading undergraduate text in this area. Complete coverage of the subject is augmented by extensive pedagogical support and opportunities for students to hone their problem solving skills.
650			_aPHARMACEUTICAL CHEMISTRY
942			_2lcc _cBK
999			_c18783 _d18783