000			01560nam a2200253Ia 4500
003			NULRC
005			20250520102818.0
008			250520s9999 xx 000 0 und d
020			_a9780123820303
040			_cNULRC
050			_aRS 403 .S55 2014
100			_aSilverman, Richard B. _eauthor
245		4	_aThe organic chemistry of drug design and drug action / _cRichard B. Silverman and Mark W. Holladay
250			_aThird edition.
260			_aSan Diego, California : _bAcademic Press, _cc2014
300			_axvii, 517 pages : _bcolor illustrations ; _c29 cm.
365			_bUSD58.98
504			_aIncludes index.
505			_aIntroduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems.
520			_a The Organic chemistry of drug design and drug action, Third edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows the reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition reflects significant changes in the process of drug design over the last decade. It preserves the successful approach of the previous editions while including significant changes in format and coverage.
650			_aPHARMACEUTICAL CHEMISTRY
700			_aHolladay, Mark W. _eco-author
942			_2lcc _cBK
999			_c15920 _d15920