000			01480nam a2200241Ia 4500
003			NULRC
005			20250520102817.0
008			250520s9999 xx 000 0 und d
020			_a9780128036204
040			_cNULRC
050			_aRM 301 .C66 2017
245		2	_aA comprehensive guide to toxicology in nonclinical drug development / _cedited by Ali S. Faqi
250			_aSecond edition.
260			_aAmsterdam : _bElsevier Science, _cc2017
300			_axiii, 971 pages : _bcolor illustrations ; _c29 cm.
365			_bPHP12021.58
504			_aIncludes bibliographical references and index.
505			_aDrug discovery, metabolism, and pharmacokinetics -- Toxicological studies and ind application, and first in-human clinical trial -- Clinical pathology, hispathology, and biomakers -- Biostatis, regulatory toxicology, and role of srudy directors -- Specialty route of administration -- Nonclinical development of monoclonal antibodies, stem cells, oncogenic and non-oncogenic drugs, olignucleotides and vaccines -- Safety evaluation of ocular drugs, botanical products, and medical devices -- Predictive toxicology, toxicmetabolimics, toxicogenomics, and imaging
520			_aIs a valuable refernces designed to provide a complete understanding of all aspects of nonclinical toxicolgy in the development of small molecules and biologics, including vaccines and botanical products.
650			_aTOXICOLOGY
700			_aFaqi, Ali S. _eeditor
942			_2lcc _cBK
999			_c15884 _d15884