000			01609nam a2200253Ia 4500
003			NULRC
005			20250520100714.0
008			250520s9999 xx 000 0 und d
020			_a9781585282418
040			_cNULRC
050			_aRM 301.5 .D57 2010
100			_aDiPiro, Joseph T. _eauthor
245		0	_aConcepts in clinical pharmacokinetics / _cJoseph T. DiPiro [and four others].
250			_aFifth edition
260			_aUnites States of America : _bAmerican Society of Civil Engineers, _cc2010
300			_axi, 248 pages : _billustrations ; _c27 cm
365			_bUSD89.34
504			_aIncludes index.
505			_aIntroduction to pharmacokinetics and pharmacodynamics -- Basic pharmacokinetics -- Half-life, elimination rate, and AUC -- Intravenous Bolus Administration, multipe drug administration, and steady-state average concentrations -- Relationships of pharmacokinetic parameters and intravenous intermittent and continous infusions -- Two-compartment models -- Biopharmaceutics : absoption -- Drug distribution and protein binding -- Drug elimination processes -- Nonlinear processes -- Pharmacokinetic variation and model-independent relationships -- Aminoglycosides -- Vancomycin -- Theophylline -- Phenytoin and digoxin
520			_aPharmacokinetics concepts are further illustrated by application to clinical dosing cases, including aminoglycocides, nacomycin, theophylline, digoxin, and phenytoin.
650			_aPHAMACOKINETICS
700			_aSpruill, William J.;Wade, William E.;Blouin, Robert A.;Preumer, Jane M. _eco-author;co-author;co-author;co-author
942			_2lcc _cBK
999			_c11955 _d11955