Principles of biochemical toxicology / John Timbrell.

Includes bibliographical references and index.

Introduction -- Dose-response relationships -- Factors affecting toxic responses: disposition -- Factors affecting toxic responses: metabolism -- Factors affecting metabolism and disposition -- Toxic responses to foreign compounds -- Biochemical mechanisms of toxicity: specific examples.

Research into the biochemical basis of toxicology has expanded rapidly over recent years, amidst concerns over the adverse effects of drugs, environmental pollution and occupational hazards.Following on from the acclaimed first two editions of Principles of Biochemical Toxicology, John Timbrell has expanded the text to include summary sections, questions and model answers and thoroughly revised artwork. These features, plus the new easy-to-read format will make biochemical toxicology more accessible to undergraduates and postgraduates coming across the subject for the first time, particularly when undertaking self-directed study.This comprehensive textbook provides a thorough explanation of dose-response relationships; disposition and metabolism; toxic responses to foreign compounds, and detailed examples to illustrate mechanisms of toxicity. There is also an expanded and updated bibliography, directing the reader to further reading if required.Students and lecturers will find the clear and concise approach, which established this book as the leading textbook in its field an essential aid to learning and teaching.