TY - BOOK AU - Patrick, Graham L. TI - An introduction to medicinal chemistry SN - 198558724 AV - RS 403 .P38 1995 PY - 1995/// CY - Oxford, United Kingdom PB - Oxford University Press KW - PHARMACEUTICAL CHEMISTRY N1 - Includes bibliographical references and index; 1.: Drugs and the medicinal chemist -- 2.: The why and the wherefore -- 3.: Protein structure -- 4.: Drug action at enzymes -- 5.: Drug action at receptors -- 6.: Nucleic acids -- 7.: Drug development -- 8.: Quantitative structure-activity relationships (QSAR) -- 10.: Antibacterial agents -- 11.: The peripheral nervous system: cholinergics anticholinergics, and anticholinesterases -- 12.: The opium alkaloids -- 13.: Cimetidine: a rational approach to drug design N2 - This illustrated text provides undergraduate and postgraduate students with an accessible introduction to medicinal chemistry. It covers basic principles and background, and then describes the general tactics and strategies employed in developing an effective drug ER -