Principles of drug action : the basis of pharmacology /
edited by William B. Pratt and Palmer Taylor
- Third edition.
- New York : Churchill Livingstone, c1990
- xiii, 836 pages : illustrations ; 27 cm.
Includes bibliographical references and index.
Molecular Basis of Pharmacologic Selectivity -- Molecular Basis of Drug Action -- The Entry, Distribution, And Elimination of Drugs -- The Time Course of Drug Action -- Pathways of Drug Metabolism -- Molecular Aspects of Regulation and Structures of the Drug- Metabolizing Enzymes -- Pharmacogenetics -- Drug Allergy -- Drug Resistance -- Drug Tolerance and Physical Dependence -- Chemical Mutagenesis -- Chemical Carcinogenesis -- Chemical Teratogenesis
An examination of how drugs affect biological organisms. It explains the principles which govern drug action, absorption, metabolism, and distribution, and is organized around systematic principles rather than drug families or drug effects.