TY  - BOOK
AU  - Silverman, Richard B.
AU  - Holladay, Mark W. 
TI  - The organic chemistry of drug design and drug action
SN  - 9780123820303
AV  - RS 403 .S55 2014 
PY  - 2014///
CY  - San Diego, California
PB  - Academic Press
KW  - PHARMACEUTICAL CHEMISTRY
N1  - Includes index; Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems
N2  -    The Organic chemistry of drug design and drug action, Third edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows the reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition reflects significant changes in the process of drug design over the last decade. It preserves the successful approach of the previous editions while including significant changes in format and coverage
ER  -