TY - BOOK AU - DiPiro, Joseph T. ;Talbert, Robert L.;Yee, Gary C.;Matzke, Gary R.;Wells, Barbara;Posey, L. Michael TI - Pharmacotherapy: a pathophysiologic approach SN - 9780071800532 AV - RM 263 .P437 2014 PY - 2014/// CY - New York PB - McGraw Hill Education KW - DRUG THERAPY N1 - Includes bibliographical references and index; Cardiovascular disorders -- Respiratory disorders -- Gastrointestinal disorders -- Renal disorders -- Neurologic disorders -- Psychiatric disorders -- Endocrinologic disorders -- Gynecologic and obstetric disorders -- Urologic disorders -- Immunologic disorders -- Rheumatologic disorders -- Ophthalmic and otolaryngological disorders -- Dermatologic disorders -- Hematologic disorders -- Infectious diseases -- Oncologic disorders -- Nutritional disorders N2 - "Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibition: Drug Development provides a concise overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce the structure, substrates, kinetics, and mechanisms of enzymes. Subsequent chapters discuss the different types of enzyme inhibitors and the principles involved in developing them into effective drugs."--Jacket ER -