Pharmacotherapy : a pathophysiologic approach /
edited by Joseph T. DiPiro [and five others]
- Ninth edition.
- New York : McGraw Hill Education, c2014
- xxxviii, 2586 pages : color illustrations ; 28 cm.
"Focusing on the development of enzyme inhibitors as therapeutic drugs, Enzymes and Their Inhibition: Drug Development provides a concise overview of the chemistry of major types of enzymes and their inhibitors. The opening chapters introduce the structure, substrates, kinetics, and mechanisms of enzymes. Subsequent chapters discuss the different types of enzyme inhibitors and the principles involved in developing them into effective drugs."--Jacket