TY  - BOOK
AU  - Shargel, Leon
AU  - Wu-Pong, Susanna;Yu, Andrew B.C
TI  - Applied biopharmaceutics and pharmacokinetics
SN  - 9781259071409
AV  - RM 301.4 .S53 2012  
PY  - 2012///
CY  - New Jersey
PB  - McGraw Hill Education
KW  - BIOPHARMACEUTICS -- PHARMACOKINETICS
N1  - Includes bibliographical references and index; Introduction to Biopharmaceutics and Pharmacokinetics -- Mathematical Fundamentals in Pharmacokinetics -- One-Compartment Open Model: Intravenous Bolus Administration -- Multicompartment Models: Intravenous Bolus Administration -- Intravenous Infusion -- Drug Elimination and Clearance -- Pharmacokinetics of Oral Absorption -- Multiple-Dosage Regimens -- Nonlinear Pharmacokinetics -- Physiologic Drug Distribution and Protein Binding -- Drug Elimination and Hepatic Clearance -- Pharmacogenetics -- Physiologic Factors Related to Drug Absorption -- Biopharmaceutic Considerations in Drug Product Design and In Vitro Drug Product Performance -- Drug Product Performance, In Vivo: Bioavailability and Bioequivalence -- Impact of Drug Product Quality and Biopharmaceutics on Clinical Efficacy -- Modified-Release Drug Products -- Targeted Drug delivery Systems and Biotechnological Products -- Relationship Between Pharmacokinetics and Pharmacodynamics -- Application of Pharmacokinetics to Clinical Situations -- Dose Adjustment in Renal and Hepatic -- Physiologic Pharmacokinetic Models, Mean Residence Time, and Statistical Moment Theory
N2  - This text integrates basic scientific principles with drug product development and clinical pharmacy practice
ER  -