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Handbook of basic pharmacokinetics-- including clinical applications / Wolfgang A. Ritschel

By: Material type: TextTextPublication details: Singapore : Info Access & Distribution Pte Ltd., c1994Edition: Fourth editionDescription: v, 588 pages : illustrations ; 19 cmISBN:
  • 9813047119
Subject(s): LOC classification:
  • RM 301.5 .R58 1994
Contents:
Definitions and Glossary -- The LADMER system-Drug liberation, absorption, distribution, metabolism, elimination and response -- Organs, tissues, cells, and organelles -- Drug receptor interactions -- Absorption/transport mechanisms -- pKa and degree of ionization -- Lipid/water partition coefficient -- Physio-chemical factors altering biological performance of drugs -- Biopharmaceutical data of the gastrointestinal tract -- Fluid compartments and circulatory system (blood and lymph) -- Binding of drugs to biological material -- Drug metabolism -- Compartment models -- Determination of rate constants -- Volume of distribution and distribution coefficient -- Excretion and clearance of drugs -- Urinary and biliary recycling -- Cumulative urinary excretion -- Area under the blood level-time curve -- Pharmacokinetics of single dose administration -- Pharmacokinetics of multiple dosing -- Compartment model independent analysis -- Drug dosage in children -- Drug dosage in elderly patients -- Drug dosage in obese patients -- Drug dosage in pregnancy -- Dosage regimen design -- Drug monitoring and dose adjustment -- Physiological and pathological factors influencing drug response -- First dose size in man -- Forensic pharmacokinetics -- Nonlinear pharmacokinetics -- Curve fitting -- Correlation of clinical response with drug disposition -- Bioavailability and bioequivalence -- Body surface area.
Summary: Pharmacokinetics, a comparatively young discipline among the health sciences, is interrelated with biopharmaceutics, pharmacology, and therapeutics.
Item type: Books - Reference
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Holdings
Item type Current library Home library Collection Call number Copy number Status Date due Barcode
Books - Reference Books - Reference National University - Manila LRC - Main Reference Nursing REF RM 301.5 .R58 1994 (Browse shelf(Opens below)) c.1 Available NULIB000015249

Includes index.

Definitions and Glossary -- The LADMER system-Drug liberation, absorption, distribution, metabolism, elimination and response -- Organs, tissues, cells, and organelles -- Drug receptor interactions -- Absorption/transport mechanisms -- pKa and degree of ionization -- Lipid/water partition coefficient -- Physio-chemical factors altering biological performance of drugs -- Biopharmaceutical data of the gastrointestinal tract -- Fluid compartments and circulatory system (blood and lymph) -- Binding of drugs to biological material -- Drug metabolism -- Compartment models -- Determination of rate constants -- Volume of distribution and distribution coefficient -- Excretion and clearance of drugs -- Urinary and biliary recycling -- Cumulative urinary excretion -- Area under the blood level-time curve -- Pharmacokinetics of single dose administration -- Pharmacokinetics of multiple dosing -- Compartment model independent analysis -- Drug dosage in children -- Drug dosage in elderly patients -- Drug dosage in obese patients -- Drug dosage in pregnancy -- Dosage regimen design -- Drug monitoring and dose adjustment -- Physiological and pathological factors influencing drug response -- First dose size in man -- Forensic pharmacokinetics -- Nonlinear pharmacokinetics -- Curve fitting -- Correlation of clinical response with drug disposition -- Bioavailability and bioequivalence -- Body surface area.

Pharmacokinetics, a comparatively young discipline among the health sciences, is interrelated with biopharmaceutics, pharmacology, and therapeutics.

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