Pharmaceutical chemistry / edited by Jill Barber and Chris Rostron.

Includes bibliographical references and index.

Machine generated contents note: 1.The importance of pharmaceutical chemistry / Jill Barber -- 1.1.Chemical structures and nomenclature -- 1.2.The human test tube -- 1.3.More test tubes: plants and microorganisms -- 1.4.Glass and plastic test tubes -- 1.5.From test tube to pharmaceutical -- 2.Organic structure and bonding / Alastair Mann -- 2.1.What is organic chemistry? -- 2.2.The shape of molecules -- 2.3.The electronic configuration of carbon -- 2.4.The shape of organic molecules -- 2.5.Intermolecular forces -- 2.6.Reaction types and the making and breaking of bonds -- 2.7.The principles of organic reaction mechanisms -- 3.Stereochemistry and drug action / Adam Todd -- 3.1.Introduction -- 3.2.Constitutional isomerism -- 3.3.Conformational isomerism -- 3.4.Stereoisomerism -- 3.5.Protein folding diseases -- 4.Properties of aliphatic hydrocarbons / Andrew J. Hall -- 4.1.Nomenclature -- 4.2.Physical properties of aliphatic hydrocarbons C 7.2.Why is aromatic chemistry important? -- 7.3.The chemistry of benzene -- 7.4.The synthesis of drugs -- 7.5.Aromatic chemistry in the body -- 8.Inorganic chemistry in pharmacy / Geoff Hall -- 8.1.Concepts in inorganic chemistry -- 8.2.Metals: introduction -- 8.3.Group 1 metals -- 8.4.Group 2 metals -- 8.5.Period 4 metals -- 8.6.Precious metals -- 8.7.Phosphorus -- 8.8.Sulfur -- 9.The chemistry of biologically important macromolecules / Alex White -- 9.1.Small molecules versus large molecules -- 9.2.Nucleic acids and nucleosides -- 9.3.Proteins -- 9.4.Carbohydrates -- 9.5.Lipids -- 10.Origins of drug molecules / Tim Snape -- 10.1.Drugs, dyes, and cleaning fluid: similarities and differences -- 10.2.Natural products as drugs and medicines -- 10.3.Semi-synthetic drugs -- 10.4.Synthetic drugs -- 10.5.Genetic engineering and fermentation (biotechnology) for the production of drugs -- 10.6.The principles of organic synthesis -- 10.7.Purification methods 11.Introduction to pharmaceutical analysis / Tony Curtis -- 11.1.Quality control of pharmaceuticals and formulated products -- 11.2.The electromagnetic spectrum -- 11.3.Ultraviolet-visible spectrophotometry -- 11.4.Infrared spectroscopy -- 11.5.Nuclear magnetic resonance (NMR) spectroscopy -- 11.6.Mass spectrometry -- 11.7.Chromatographic methods of analysis -- 11.8.Gas-liquid chromatography -- 12.The molecular characteristics of good drugs / Jill Barber -- 12.1.Rules in chemistry -- 12.2.The Rule of Five -- an empirical rule -- 12.3.Structure-activity relationships -- 12.4.Stereochemistry -- 12.5.Purity -- Index.

This volume provides a wide-ranging overview of organic chemistry as applied to the study and practice of pharmacy. Drugs are simply chemicals, so to fully understand their manufacture, formulation, and the way they work in our bodies, an understanding of organic compounds and their reactions is essential. Taking medication is a common occurrence for many people, whether it is to soothe an aching head, regulate blood sugars, or treat life-threatening conditions such as HIV or cancer. Examining how drugs are manufactured, formulated, and the way that they work in our bodies, Pharmaceutical Chemistry provides a wide-ranging overview of organic chemistry as it is applied to the study and practice of pharmacy. FEATURES * Supports an integrated pharmacy education * Focuses on the fundamental ideas that first-year students need to fully grasp before progressing in their studies * Demonstrates the connections between scientific concepts and principles and how they are applied to pharmacy * Written and edited by experts who have a wealth of teaching experience