Organic chemistry / (Record no. 6114)

MARC details
000 -LEADER
fixed length control field 03080nam a2200241Ia 4500
003 - CONTROL NUMBER IDENTIFIER
control field NULRC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250520094919.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 250520s9999 xx 000 0 und d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 471190950
040 ## - CATALOGING SOURCE
Transcribing agency NULRC
050 ## - LIBRARY OF CONGRESS CALL NUMBER
Classification number QD 253 .S65 1998
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Solomons, T. W. Graham.
Relator term author
245 #0 - TITLE STATEMENT
Title Organic chemistry /
Statement of responsibility, etc. T W Graham Solomons and Craig B Fryhle
250 ## - EDITION STATEMENT
Edition statement Seventh edition.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. New York :
Name of publisher, distributor, etc. Wiley,
Date of publication, distribution, etc. c2000
300 ## - PHYSICAL DESCRIPTION
Extent 1 volume (various pagings) :
Other physical details color illustrations ;
Dimensions 27 cm.
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc. note Includes bibliographical references and index.
505 ## - FORMATTED CONTENTS NOTE
Formatted contents note Carbon compounds and chemical bonds -- Representative carbon compounds: funtional groups, intermolecular forces, and infrared (IR) spectroscopy -- An introduction to organic reactions: acids and bases -- Alkanes: nomenclature, conformational analysis, and an introduction to synthesis -- Stereochemistry: chiral molecules -- Ionic reactions--nucleophilic substitution and elimination reactions of alkyl halides -- Alkenes and alkynes I: properties and synthesis. Elimination reactions of alkyl halides -- Alkenes and alkynes II: addition reactions -- Nuclear magnetic resonance and mass spectrometry: tools for structure determination -- Radical reactions -- Alcohols and ethers -- Alcohols from carbonyl compounds. Oxidation--reduction and organometallic compounds -- Conjugated unsaturated systems -- Aromatic compounds -- Reactions of aromatic compounds. Aldehydes and ketones I: nucleophilic addition to the carbonyl group -- Aldehydes and ketones II. aldol reactions -- Carboxylic acids and their derivatives. Nucleophilic addition-elimination at the acyl carbon -- Synthesis and reactions of B-dicarbonyl compounds: more chemistry of enolate ions -- Amines -- Phenols and aryl halides: nucleopholic aromatic substitution -- Carbohydrates -- Lipids -- Amino acids and proteins -- Nucleic acids and protein synthesis.
520 ## - SUMMARY, ETC.
Summary, etc. On the cover of this book is a Pacific yew tree, found in the ancient forests of the Pacific Northwest. The bark of the Pacific yew tree produces Taxol, found to be a highly effective drug against ovarian and breast cancer. Taxol blocks mitosis during eukaryotic cell division. The supply of Taxol from the Pacific yew tree is vanishingly small, however. A single 100-year-old tree provides only about one dose of the drug (roughly 300 mg). For this reason, as well as the spectacular molecular architecture of Taxol, synthetic organic chemists fiercely undertook efforts to synthesize it. Five total syntheses of Taxol have thus far been reported. Now, a combination of isolation of a related metabolite from European yew needles, and synthesis of Taxol from that intermediate, supply the clinical demand. This case clearly demonstrates the importance of synthesis and the use of organic chemistry. It's just one of the many examples used in the text that will spark the interest of students and get them involved in the study of organic chemistry!
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element CHEMISTRY, ORGANIC
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Fryhle, Craig B.
Relator term co-author
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Library of Congress Classification
Koha item type Books
Holdings
Withdrawn status Lost status Source of classification or shelving scheme Damaged status Not for loan Collection Home library Current library Shelving location Date acquired Source of acquisition Total checkouts Full call number Barcode Date last seen Copy number Price effective from Koha item type
    Library of Congress Classification     Pharmacy LRC - Main National University - Manila General Circulation 02/29/2012 Reaccessioned   GC QD 253 .S65 1998 NULIB000003873 05/20/2025 c.1 05/20/2025 Books