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07735nam a2200241Ia 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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NULRC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20250520094918.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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250520s9999 xx 000 0 und d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
683305034 |
| 040 ## - CATALOGING SOURCE |
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| Transcribing agency |
NULRC |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QP 518.3 .B56 1999 |
| 245 #0 - TITLE STATEMENT |
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| Title |
Biochemistry / |
| Statement of responsibility, etc. |
edited by Victor L. Davidson and Donald B. Stittman |
| 250 ## - EDITION STATEMENT |
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| Edition statement |
Fourth edition. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Place of publication, distribution, etc. |
Baltimore, Maryland : |
| Name of publisher, distributor, etc. |
Lippincott Williams & Wilkins, |
| Date of publication, distribution, etc. |
c1999 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
xiii, 479 pages : |
| Other physical details |
illustrations ; |
| Dimensions |
26 cm. |
| 500 ## - GENERAL NOTE |
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| General note |
Revised edition of: Biochemistry / Victor L. Davidson, Donald B. Sittman. 3rd ed. c1994. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Includes bibliographical references and index. |
| 505 ## - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
Preface xi Acknowledgments xiii Section I Structure and Function of the Major Cell Components Water, Acid--Base Equilibria, and Blood pH 1 (10) Water 1 (1) Acid--base equilibrium 2 (3) Regulation of blood pH 5 (6) Amino Acid and Protein Structure 11 (18) Nature of proteins 11 (1) Amino acids 12 (3) Peptides and polypeptides 15 (1) Conformation of proteins 16 (3) Purification of proteins 19 (10) Protein Structure--Function Relationships 29 (30) Introduction 29 (1) Oxygen transport proteins 29 (9) Albumin 38 (1) Humoral immunity 39 (3) Collagen 42 (6) Muscle contraction 48 (11) Enzymes 59 (18) General characteristics of enzymes 59 (1) Mechanism of enzyme catalysis 60 (1) Enzyme kinetics 61 (2) Enzyme inhibition 63 (2) Regulation of enzymes 65 (1) Enzymes in clinical diagnosis 66 (1) Blood clotting 67 (3) Regulation of clotting 70 (1) Drugs that affect clotting 71 (6) Carbohydrate Function and Structure 77 (12) Carbohydrate functions 77 (1) Carbohydrate classification and nomenclature 77 (1) Structures 78 (1) Glycosidic linkages 79 (2) Carbohydrate derivatives 81 (1) Glycoproteins 81 (2) Blood group antigens 83 (6) Nucleic Acids 89 (16) Nucleic acids are polymers of nucleotides 89 (2) DNA secondary structure 91 (5) Higher order (tertiary) structure of DNA 96 (2) RNA structure 98 (7) Lipids and Related Compounds 105 (14) Nature of lipids 105 (1) Fatty acids 105 (2) Phospholipids 107 (1) Sphingolipids 108 (1) Eicosanoids 109 (3) Steroids 112 (2) Plasma lipoproteins 114 (5) Section II Storage and Expression of Genetic Information DNA Replication and Repair 119 (26) The structure of DNA reveals a mechanism for its replication 119 (1) Prokaryotic replication 119 (7) Eukaryotic replication 126 (4) Drugs that affect replication 130 (2) Mutations 132 (2) DNA repair 134 (11) RNA Synthesis and Processing 145 (20) Major classes of ribonucleic acid (RNA) 145 (2) Transcription 147 (7) Post-transcriptional RNA processing 154 (11) Translation of mRNA: Protein Synthesis 165 (20) Introduction 165 (1) Activation of amino acids: formation of aminoacyl-transfer RNAs (tRNAs) 166 (1) Codon--anticodon recognition 167 (2) Structure of ribosomes 169 (1) Protein synthesis in prokaryotes 170 (5) Protein synthesis in eukaryotes 175 (2) Protein synthesis on the endoplasmic reticulum 177 (1) Drugs and inhibitors of protein synthesis in eukaryotes 178 (7) Recombinant DNA 185 (22) Introduction 185 (1) Tools of recombinant DNA 185 (2) Cloning 187 (8) Major analytic techniques 195 (12) Regulation of Gene Expression 207 (28) Prokaryotes: the operon model for the regulation of gene expression 207 (3) General control of operons 210 (2) Control by attenuation 212 (3) Introduction to regulation of gene expression in eukaryotes 215 (1) Transcriptional regulation 215 (3) Post-transcriptional regulation 218 (3) Translational regulation 221 (1) Alterations in gene content or position 222 (13) Section III Metabolism Introduction to Metabolism 235 (12) Metabolism 235 (1) Compartmentalization of metabolic pathways in cells 235 (3) Bioenergetics 238 (1) High-energy phosphate compounds 239 (1) Oxidation--reduction reactions 240 (2) Monitoring metabolic events in tissues 242 (5) Vitamins and Minerals 247 (12) Overview 247 (1) Water-soluble vitamins 248 (4) Fat-soluble vitamins 252 (2) Minerals 254 (5) Mechanisms of Hormone Action 259 (14) Overview 259 (1) Hydrophilic hormones 260 (5) Lipophilic hormones 265 (8) Glycolysis 273 (14) Overview of glycolysis 273 (1) Carbohydrate digestion 273 (2) Embden-Meyerhof pathway (glycolysis) 275 (3) ATP production 278 (2) Disorders associated with impaired glycolysis 280 (1) Fates of pyruvate 280 (1) Lactic acidosis 281 (6) Alternative Pathways of Carbohydrate Metabolism 287 (14) Pentose phosphate pathway (hexose monophosphate shunt) 287 (2) Uronic acid pathway (glucuronic acid cycle) 289 (1) Metabolism of fructose 289 (3) Metabolism of galactose 292 (1) Sorbitol metabolism in diabetes 293 (1) Formation of amino sugars 293 (1) Ethanol metabolism 293 (8) Pyruvate Dehydrogenase and Citric Acid Cycle 301 (10) The pyruvate dehydrogenase (PDH) enzyme complex 301 (2) Overview of the citric acid cycle 303 (1) Reactions of the citric acid cycle 304 (2) Anaplerotic reactions 306 (5) Mitochondrial Electron Transport and Oxidative Phosphorylation 311 (12) The electron transport (respiratory) chain 311 (3) Oxidative phosphorylation 314 (2) Coupling of phosphorylation to respiration 316 (1) Disorders of mitochondrial oxidative phosphorylation 316 (1) Superoxide metabolism 317 (6) Gluconeogenesis 323 (10) Overview of gluconeogenesis 323 (1) Substrates for gluconeogenesis 323 (2) Reactions of gluconeogenesis 325 (2) Diseases associated with defects of gluconeogenesis 327 (1) Control of gluconeogenesis 328 (5) Glycogen Metabolism 333 (10) Glycogen 333 (1) Glycogenesis 333 (2) Glycogenolysis 335 (1) Phosphorylation cascades 335 (2) Regulation of glycogen metabolism 337 (1) Glycogen storage diseases 337 (6) Fatty Acid Metabolism 343 (14) Biosynthesis of fatty acids 343 (3) Fatty acid oxidation 346 (3) Triacylglycerols (triglycerides) 349 (2) Ketone body metabolism 351 (6) Metabolism of Lipids and Related Compounds 357 (16) Metabolism of phosphoglycerides 357 (2) Metabolism of sphingolipids 359 (1) Metabolism of eicosanoids 360 (1) Steroid metabolism 361 (4) Lipoprotein metabolism 365 (8) Amino Acid Degradation 373 (16) Proteolysis 373 (2) Amino acid pool 375 (1) Metabolic flow of amino acid nitrogen 376 (3) Classification of amino acids 379 (1) Fate of carbon skeletons 379 (5) Inherited disorders of amino acid catabolism 384 (5) Biosynthesis of Amino Acids and Amino Acid--Derived Compounds 389 (14) Biosynthesis of amino acids 389 (1) Amino acids as major inputs to the one-carbon pool 390 (2) Tyrosine-derived biologically important compounds 392 (2) Tryptophan-derived biologically important compounds 394 (1) Glutathione 395 (1) Biosynthesis of other amino acid--derived compounds 395 (1) Heme metabolism 396 (7) Nucleotide Metabolism 403 (22) Synthesis of purine and pyrimidine nucleotides 403 (7) Deoxyribonucleotides 410 (1) Degradation of purine and pyrimidine nucleotides 411 (2) Biosynthesis of nucleotide coenzymes 413 (2) Inhibitors of purine and pyrimidine metabolism 415 (3) Diseases associated with defects of nucleotide metabolism 418 (7) Integration of Metabolism 425 (12) Metabolic fuels 425 (1) Use of metabolic fuels 425 (3) The flow of key metabolic intermediates between different pathways 428 (1) Metabolism of specialized tissues 428 (3) Adaptations during starvation 431 (1) Diabetes mellitus 431 (6) Comprehensive Exam 437 (28) Index 465 |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
NMS Biochemistry, Fourth Edition, is designed to help medical students successfully complete a course in biochemistry and prepare for USMLE Step 1. This new edition has been significantly updated, and extensively rewritten to emphasize medical relevance. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
BIOCHEMISTRY -- OUTLINES, SYLLABI, ETC |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Personal name |
Davidson, Victor L. ;Stittman, Donald B. |
| Relator term |
editor;co-editor |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
Library of Congress Classification |
| Koha item type |
Books |
